Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Regulator of chromosome condensation, RCC1
- Armadillo
- Importin-alpha, importin-beta-binding domain
- Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II
- Atypical Arm repeat
- Armadillo-like helical
- Importin-alpha, importin-beta-binding domain superfamily
- Armadillo-type fold
1 more domain
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149439 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Guanine nucleotide exchange factor SRM1
Molecule details ›
Chain: A
Length: 482 amino acids
Theoretical weight: 53.08 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 482 amino acids
Theoretical weight: 53.08 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
- Canonical:
P21827 (Residues: 1-482; Coverage: 100%)
Sequence domains:
- Regulator of chromosome condensation (RCC1) repeat
- Regulator of chromosome condensation (RCC1) repeat
Importin subunit alpha
Molecule details ›
Chain: B
Length: 542 amino acids
Theoretical weight: 60.5 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
Sequence domains:
Structure domains: Leucine-rich Repeat Variant
Length: 542 amino acids
Theoretical weight: 60.5 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli
UniProt:
- Canonical: Q02821 (Residues: 1-542; Coverage: 100%)
Sequence domains:
Structure domains: Leucine-rich Repeat Variant
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
SSRL BEAMLINE BL14-1
Spacegroup:
P212121
Expression system: Escherichia coli
