Function and Biology Details
Reaction catalysed:
GTP + H(2)O = GDP + phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Small GTPase
- P-loop containing nucleoside triphosphate hydrolase
- GMP phosphodiesterase, delta subunit
- Immunoglobulin E-set
- GMP phosphodiesterase, delta subunit superfamily
- Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit
- Small GTPase, Ras-type
- Small GTP-binding protein domain
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-129172 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
GTPase KRas
Molecule details ›
Chains: A, C
Length: 185 amino acids
Theoretical weight: 21.06 KDa
Source organism: Homo sapiens
Expression system: unidentified baculovirus
UniProt:
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases
Length: 185 amino acids
Theoretical weight: 21.06 KDa
Source organism: Homo sapiens
Expression system: unidentified baculovirus
UniProt:
- Canonical:
P01116 (Residues: 2-186; Coverage: 97%)
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta
Molecule details ›
Chains: B, D
Length: 150 amino acids
Theoretical weight: 17.44 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: GMP-PDE, delta subunit
Structure domains: GMP phosphodiesterase, delta subunit
Length: 150 amino acids
Theoretical weight: 17.44 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: O43924 (Residues: 1-150; Coverage: 100%)
Sequence domains: GMP-PDE, delta subunit
Structure domains: GMP phosphodiesterase, delta subunit
