Function and Biology Details
Reaction catalysed:
ADP + phosphate + acetyl-CoA + oxaloacetate = ATP + citrate + CoA
Biochemical function:
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domains:
- Succinyl-CoA synthetase-like
- CoA-binding
- ATP-citrate lyase/succinyl-CoA ligase, active site
- ATP-citrate lyase/succinyl-CoA ligase, conserved site
- ATP-citrate synthase/succinyl-CoA ligase, C-terminal domain
- NAD(P)-binding domain superfamily
- Citrate synthase
- Succinyl-CoA synthetase, beta subunit, conserved site
1 more domain
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
ATP-citrate synthase (preferred)
PDBe Complex ID:
PDB-CPX-156797 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ATP-citrate synthase
Molecule details ›
Chains: A, B
Length: 828 amino acids
Theoretical weight: 90.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 828 amino acids
Theoretical weight: 90.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P53396 (Residues: 1-817; Coverage: 74%)
Sequence domains:
