› 5tkk

X-ray diffraction
1.55Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-209064 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Transmembrane protein gp41 Chain: A
Molecule details ›
Chain: A
Length: 8 amino acids
Theoretical weight: 733 Da
Source organism: Human immunodeficiency virus 1
Expression system: Not provided
UniProt:
  • Canonical: P04578 (Residues: 512-519; Coverage: 1%)
Gene name: env
mouse antibody vFP5.01 heavy chain Chain: H
Molecule details ›
Chain: H
Length: 222 amino acids
Theoretical weight: 24.36 KDa
Source organism: Mus musculus
Expression system: Mus musculus
Structure domains: Immunoglobulins
mouse antibody vFP5.01 light chain Chain: L
Molecule details ›
Chain: L
Length: 214 amino acids
Theoretical weight: 23.7 KDa
Source organism: Mus musculus
Expression system: Mus musculus
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P21
Unit cell:
a: 36.237Å b: 82.233Å c: 72.264Å
α: 90° β: 90.22° γ: 90°
R-values:
R R work R free
0.211 0.209 0.247
Expression systems:
  • Not provided
  • Mus musculus

Quick links

Citations

35 review citations

Vaccines and Broadly Neutralizing Antibodies for HIV-1 Prevention.
Stephenson et al. (2020)
34 more

2 mentions without citation

Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1.
Xu et al. (2018)
1 more