› 5tp5

Solution NMR

Solution structure of the calcium deficient mutant calmodulin CaM1234

Released:
DOI: 10.2210/pdb5tp5/pdb
PDB entry 5tp5 coloured by chain, ensemble of 20 models, front view.
PDB entry 5tp5 coloured by chain, ensemble of 20 models, side view.
PDB entry 5tp5 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Structural Consequences of Calmodulin EF Hand Mutations.
Piazza M, Taiakina V, Dieckmann T, Guillemette JG
Biochemistry 56 944-956 (2017)
PMID: 28121131

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-143908 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calmodulin-1 Chain: A
Molecule details ›
Chain: A
Length: 148 amino acids
Theoretical weight: 16.55 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P0DP23 (Residues: 2-149; Coverage: 99%)
Gene names: CALM, CALM1, CAM, CAM1
Sequence domains: EF-hand domain pair

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 59%
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Small-conductance Ca2+-activated K+ channels: insights into their roles in cardiovascular disease.
Gu et al. (2018)
1 more