› 5tps

X-ray diffraction
2.7Å resolution

Structure of a Fc heterodimer

Released:
DOI: 10.2210/pdb5tps/pdb
PDB entry 5tps coloured by chain, front view.
PDB entry 5tps coloured by chain, side view.
PDB entry 5tps coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Zhou A, Wei H

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134813 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (4 distinct):
Immunoglobulin heavy constant gamma 1 Chain: B
Molecule details ›
Chain: B
Length: 243 amino acids
Theoretical weight: 27 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P01857 (Residues: 104-328; Coverage: 56%)
Gene name: IGHG1
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
Immunoglobulin heavy constant gamma 1 Chain: A
Molecule details ›
Chain: A
Length: 232 amino acids
Theoretical weight: 25.94 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P01857 (Residues: 104-328; Coverage: 56%)
Gene name: IGHG1
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN, GAL
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, BMA, MAN, GAL, FUC
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P212121
Unit cell:
a: 49.26Å b: 79.52Å c: 137.98Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.206 0.202 0.271
Expression system: Homo sapiens

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