› 5tsv

X-ray diffraction
2.5Å resolution

HIV-1 CA hexamer with NUP153 peptide - R3 crystal form

Released:
DOI: 10.2210/pdb5tsv/pdb
PDB entry 5tsv coloured by chain, front view.
PDB entry 5tsv coloured by chain, side view.
PDB entry 5tsv coloured by chain, top view.
Source organisms:
Entry authors: Skorupka K, Ganser-Pornillos BK, Pornillos O

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero nonamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146191 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Capsid protein p24 Chains: A, B
Molecule details ›
Chains: A, B
Length: 231 amino acids
Theoretical weight: 25.46 KDa
Source organism: Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P12493 (Residues: 133-363; Coverage: 46%)
Gene name: gag
Sequence domains:
Nuclear pore complex protein Nup153 Chain: D
Molecule details ›
Chain: D
Length: 23 amino acids
Theoretical weight: 2.21 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P49790 (Residues: 1407-1429; Coverage: 2%)
Gene name: NUP153

Ligands and Environments

1 bound ligand:
Ligand FLU 1 x FLU
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-D
Spacegroup: R3
Unit cell:
a: 151.924Å b: 151.924Å c: 69.646Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.208 0.204 0.251
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided

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