› 5tsx

X-ray diffraction
1.9Å resolution

HIV-1 CA hexamer with NUP153 peptide - P1 crystal form

Released:
DOI: 10.2210/pdb5tsx/pdb
PDB entry 5tsx coloured by chain, front view.
PDB entry 5tsx coloured by chain, side view.
PDB entry 5tsx coloured by chain, top view.
Source organisms:
Entry authors: Skorupka K, Ganser-Pornillos BK, Pornillos O

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero nonamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146191 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Capsid protein p24 Chains: A, B, C, D, E, F, G, H, I, J, K, L
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L
Length: 231 amino acids
Theoretical weight: 25.46 KDa
Source organism: Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P12493 (Residues: 133-363; Coverage: 46%)
Gene name: gag
Sequence domains:
Nuclear pore complex protein Nup153 Chains: M, N, O, P, R, T
Molecule details ›
Chains: M, N, O, P, R, T
Length: 23 amino acids
Theoretical weight: 2.21 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P49790 (Residues: 1407-1429; Coverage: 2%)
Gene name: NUP153

Ligands and Environments

1 bound ligand:
Ligand FLU 4 x FLU
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-D
Spacegroup: P1
Unit cell:
a: 57.333Å b: 91.487Å c: 150.047Å
α: 89.54° β: 90.49° γ: 96.08°
R-values:
R R work R free
0.187 0.185 0.228
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided

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