› 5tzm

X-ray diffraction
1.18Å resolution

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178427 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Obscurin Chain: A
Molecule details ›
Chain: A
Length: 100 amino acids
Theoretical weight: 10.71 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q5VST9 (Residues: 4431-4521; Coverage: 1%)
Gene names: KIAA1556, KIAA1639, OBSCN
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P3121
Unit cell:
a: 60.98Å b: 60.98Å c: 47.56Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.165 0.164 0.185
Expression system: Escherichia coli BL21

Quick links

Citations

6 review citations

A mutation update for the FLNC gene in myopathies and cardiomyopathies.
Verdonschot et al. (2020)
5 more

2 mentions without citation

A novel FLNC frameshift and an OBSCN variant in a family with distal muscular dystrophy.
Rossi et al. (2017)
1 more