› 5ujl

Solution NMR

Representative 1-conformer ensembles of K27-linked Ub2 from RDC data

Released:
DOI: 10.2210/pdb5ujl/pdb
PDB entry 5ujl coloured by chain, ensemble of 2 models, front view.
PDB entry 5ujl coloured by chain, ensemble of 2 models, side view.
PDB entry 5ujl coloured by chain, ensemble of 2 models, top view.
Source organism: Homo sapiens
Primary publication:
Linkage via K27 Bestows Ubiquitin Chains with Unique Properties among Polyubiquitins.
Castañeda CA, Dixon EK, Walker O, Chaturvedi A, Nakasone MA, Curtis JE, Reed MR, Krueger S, Cropp TA, Fushman D
Structure 24 423-36 (2016)
PMID: 26876099

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-143296 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ubiquitin Chains: A, B
Molecule details ›
Chains: A, B
Length: 76 amino acids
Theoretical weight: 8.58 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P0CG47 (Residues: 153-228; Coverage: 33%)
Gene name: UBB
Sequence domains: Ubiquitin family

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 7%
Refinement method: na
Expression system: Escherichia coli

Quick links

Citations

10 review citations

The recognition of ubiquitinated proteins by the proteasome.
Grice et al. (2016)
9 more

1 mention without citation

K27-linked ubiquitylation promotes p97 substrate processing and is essential for cell proliferation.
Shearer et al. (2022)