Function and Biology Details
Reactions catalysed:
ATP + a protein = ADP + a phosphoprotein
GTP + H(2)O = GDP + phosphate
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132118 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Serine/threonine-protein kinase PAK 4
Molecule details ›
Chain: A
Length: 48 amino acids
Theoretical weight: 5.65 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
Sequence domains: P21-Rho-binding domain
Length: 48 amino acids
Theoretical weight: 5.65 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
- Canonical:
O96013 (Residues: 1-45; Coverage: 8%)
Sequence domains: P21-Rho-binding domain
Serine/threonine-protein kinase PAK 4
Molecule details ›
Chain: B
Length: 346 amino acids
Theoretical weight: 39.12 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
Sequence domains: Protein kinase domain
Length: 346 amino acids
Theoretical weight: 39.12 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
- Canonical: O96013 (Residues: 286-591; Coverage: 52%)
Sequence domains: Protein kinase domain
Cell division control protein 42 homolog
Molecule details ›
Chain: C
Length: 185 amino acids
Theoretical weight: 20.73 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases
Length: 185 amino acids
Theoretical weight: 20.73 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
- Canonical: P60953 (Residues: 1-177; Coverage: 93%)
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases
