› 5v54

X-ray diffraction
3.9Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151175 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
5-hydroxytryptamine receptor 1B Chains: A, B
Molecule details ›
Chains: A, B
Length: 395 amino acids
Theoretical weight: 44.97 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P28222 (Residues: 37-239, 240-250, 251-279, 280-291, 292-296, 297-300, 301-390; Coverage: 91%)
Gene names: HTR1B, HTR1DB
Sequence domains: 7 transmembrane receptor (rhodopsin family)

Ligands and Environments

1 bound ligand:
Ligand 89F 2 x 89F
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: C2
Unit cell:
a: 235.2Å b: 48.83Å c: 139.22Å
α: 90° β: 124.07° γ: 90°
R-values:
R R work R free
0.273 0.272 0.288
Expression system: Spodoptera frugiperda

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