Function and Biology Details
Reaction catalysed:
UDP-N-acetyl-alpha-D-glucosamine + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-N-Asn-[protein] = UDP + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-(beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-N-Asn-[protein]
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171224 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
Molecule details ›
Chains: A, B
Length: 419 amino acids
Theoretical weight: 48.35 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: N-acetylglucosaminyltransferase II (MGAT2)
Length: 419 amino acids
Theoretical weight: 48.35 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
Q10469 (Residues: 29-447; Coverage: 94%)
Sequence domains: N-acetylglucosaminyltransferase II (MGAT2)
Ligands and Environments
No modified residues
Experiments and Validation Details
X-ray source:
APS BEAMLINE 22-ID
Expression system: Homo sapiens
