Function and Biology Details
Biochemical function:
- not assigned
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
Amyloid-beta protein 40/42 complex (preferred)
PDBe Complex ID:
PDB-CPX-138356 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Immunoglobulin gamma-1 heavy chain
Molecule details ›
Chain: H
Length: 220 amino acids
Theoretical weight: 23 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Structure domains: Immunoglobulins
Length: 220 amino acids
Theoretical weight: 23 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P0DOX5 (Residues: 1-227; Coverage: 49%)
Structure domains: Immunoglobulins
Ig-like domain-containing protein
Molecule details ›
Chain: L
Length: 219 amino acids
Theoretical weight: 24.06 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Structure domains: Immunoglobulins
Length: 219 amino acids
Theoretical weight: 24.06 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: Q0KKI6 (Residues: 1-219; Coverage: 100%)
Structure domains: Immunoglobulins
P3(40)
Molecule details ›
Chain: A
Length: 15 amino acids
Theoretical weight: 1.76 KDa
Source organism: Homo sapiens
Expression system: unidentified
UniProt:
Sequence domains: Beta-amyloid peptide (beta-APP)
Length: 15 amino acids
Theoretical weight: 1.76 KDa
Source organism: Homo sapiens
Expression system: unidentified
UniProt:
- Canonical: P05067 (Residues: 682-696; Coverage: 2%)
Sequence domains: Beta-amyloid peptide (beta-APP)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
SSRL BEAMLINE BL11-1
Spacegroup:
P212121
Expression systems:
- Escherichia coli
- unidentified
