Function and Biology Details
Reaction catalysed:
[a protein]-serine/threonine phosphate + H(2)O = [a protein]-serine/threonine + phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-151667 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
Molecule details ›
Chains: A, D, G, J
Length: 585 amino acids
Theoretical weight: 65.7 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: HEAT repeat
Structure domains: Leucine-rich Repeat Variant
Length: 585 amino acids
Theoretical weight: 65.7 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P30153 (Residues: 9-589; Coverage: 99%)
Sequence domains: HEAT repeat
Structure domains: Leucine-rich Repeat Variant
TIP41-like protein
Molecule details ›
Chains: B, E, H, K
Length: 251 amino acids
Theoretical weight: 29.04 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
Sequence domains: TIP41-like family
Length: 251 amino acids
Theoretical weight: 29.04 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
- Canonical: Q8BH58 (Residues: 12-259; Coverage: 92%)
Sequence domains: TIP41-like family
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
Molecule details ›
Chains: C, F, I, L
Length: 311 amino acids
Theoretical weight: 35.78 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Sequence domains: Calcineurin-like phosphoesterase
Structure domains: Purple Acid Phosphatase; chain A, domain 2
Length: 311 amino acids
Theoretical weight: 35.78 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical: P67775 (Residues: 1-309; Coverage: 100%)
Sequence domains: Calcineurin-like phosphoesterase
Structure domains: Purple Acid Phosphatase; chain A, domain 2
