› 5w5h

X-ray diffraction
2.79Å resolution

Human IFIT1 dimer with m7Gppp-AAAA

Released:
DOI: 10.2210/pdb5w5h/pdb
PDB entry 5w5h coloured by chain, front view.
PDB entry 5w5h coloured by chain, side view.
PDB entry 5w5h coloured by chain, top view.
Source organisms:
Entry authors: Abbas YM, Martinez-Montero S, Damha MJ, Nagar B

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
hetero tetramer (preferred)
hetero hexadecamer
Assembly name:
PDBe Complex ID:
PDB-CPX-140812 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct RNA molecule
Macromolecules (2 distinct):
Interferon-induced protein with tetratricopeptide repeats 1 Chains: A, C
Molecule details ›
Chains: A, C
Length: 479 amino acids
Theoretical weight: 55.53 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P09914 (Residues: 1-478; Coverage: 100%)
Gene names: G10P1, IFI56, IFIT1, IFNAI1, ISG56
Sequence domains:
RNA (5'-D(*(GTA))-R(P*AP*AP*A)-3') Chains: B, D
Molecule details ›
Chains: B, D
Length: 4 nucleotides
Theoretical weight: 1.71 KDa
Source organism: unidentified
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: I4
Unit cell:
a: 184.355Å b: 184.355Å c: 88.762Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.22 0.219 0.241
Expression systems:
  • Escherichia coli
  • Not provided

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