› 5w72

Solution NMR

Impact of IR active probes on PDZ3 and its ligand binding studied by NMR and X-ray crystallography

Released:
DOI: 10.2210/pdb5w72/pdb
PDB entry 5w72 coloured by chain, ensemble of 20 models, front view.
PDB entry 5w72 coloured by chain, ensemble of 20 models, side view.
PDB entry 5w72 coloured by chain, ensemble of 20 models, top view.
Source organism: Rattus norvegicus
Primary publication:
Impact of Azidohomoalanine Incorporation on Protein Structure and Ligand Binding.
Lehner F, Kudlinzki D, Richter C, Müller-Werkmeister HM, Eberl KB, Bredenbeck J, Schwalbe H, Silvers R
Chembiochem 18 2340-2350 (2017)
PMID: 28950050

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151877 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Disks large homolog 4 Chain: A
Molecule details ›
Chain: A
Length: 102 amino acids
Theoretical weight: 11.01 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P31016 (Residues: 301-402; Coverage: 14%)
Gene names: Dlg4, Dlgh4, Psd95
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain

Ligands and Environments

No bound ligands
1 modified residue:
Ligand AZH 1 x AZH

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 79%
Refinement method: torsion angle dynamics
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 review citations

Next-generation physiology approaches to study microbiome function at single cell level.
Hatzenpichler et al. (2020)
1 more