› 5w93

X-ray diffraction
2Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178860 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Breast cancer anti-estrogen resistance protein 1 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 137 amino acids
Theoretical weight: 14.8 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q61140 (Residues: 738-874; Coverage: 16%)
Gene names: Bcar1, Cas, Crkas
Sequence domains: Crk-Associated Substrate C-terminal domain
Structure domains: Alpha-catenin/vinculin-like
Paxillin Chains: D, E, F
Molecule details ›
Chains: D, E, F
Length: 20 amino acids
Theoretical weight: 2.18 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
  • Canonical: Q8VI36 (Residues: 1-20; Coverage: 3%)
Gene name: Pxn

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-BM
Spacegroup: C2
Unit cell:
a: 84.29Å b: 37.741Å c: 152.502Å
α: 90° β: 100.94° γ: 90°
R-values:
R R work R free
0.198 0.196 0.237
Expression systems:
  • Escherichia coli
  • Not provided

Quick links

Citations

4 review citations

Regulation of Transmembrane Signaling by Phase Separation.
Case et al. (2019)
3 more

1 mention without citation

Structural and functional insights into the interaction between the Cas family scaffolding protein p130Cas and the focal adhesion-associated protein paxillin.
Zhang et al. (2017)