Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-208420 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Tumor necrosis factor, soluble form
Molecule details ›
Chains: E, F, G
Length: 157 amino acids
Theoretical weight: 17.37 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli-Pichia pastoris shuttle vector pPpARG4
UniProt:
Sequence domains: TNF(Tumour Necrosis Factor) family
Structure domains: Jelly Rolls
Length: 157 amino acids
Theoretical weight: 17.37 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli-Pichia pastoris shuttle vector pPpARG4
UniProt:
- Canonical:
P01375 (Residues: 77-233; Coverage: 67%)
Sequence domains: TNF(Tumour Necrosis Factor) family
Structure domains: Jelly Rolls
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
PAL/PLS BEAMLINE 7A (6B, 6C1)
Spacegroup:
C2
Expression systems:
- Escherichia coli-Pichia pastoris shuttle vector pPpB1GAP_S
- Escherichia coli-Pichia pastoris shuttle vector pPpARG4
