› 5wwi

X-ray diffraction
3.19Å resolution

Crystal Structure of HLA-A*2402 in complex with avian influenza A(H7N9) virus-derived peptide H7-25 (data set 1)

Released:
DOI: 10.2210/pdb5wwi/pdb
PDB entry 5wwi coloured by chain, front view.
PDB entry 5wwi coloured by chain, side view.
PDB entry 5wwi coloured by chain, top view.
Source organisms:
Entry authors: Zhao M, Liu K, Chai Y, Qi J, Liu J, Gao GF

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-102819 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
HLA class I histocompatibility antigen, A alpha chain Chain: A
Molecule details ›
Chain: A
Length: 274 amino acids
Theoretical weight: 31.55 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P04439 (Residues: 25-298; Coverage: 80%)
Gene names: HLA-A, HLAA
Sequence domains:
Structure domains:
Beta-2-microglobulin Chain: B
Molecule details ›
Chain: B
Length: 100 amino acids
Theoretical weight: 11.82 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P61769 (Residues: 20-119; Coverage: 100%)
Gene names: B2M, CDABP0092, HDCMA22P
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
Matrix protein 1 Chain: E
Molecule details ›
Chain: E
Length: 11 amino acids
Theoretical weight: 1.46 KDa
Source organism: Influenza A virus (A/chicken/China/028/2014(H7N9))
Expression system: Not provided
UniProt:
  • Canonical: A0A0X9JHC1 (Residues: 99-109; Coverage: 4%)
Gene names: M, M1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P212121
Unit cell:
a: 67.444Å b: 79.004Å c: 88.048Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.196 0.189 0.31
Expression systems:
  • Escherichia coli
  • Not provided

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