Function and Biology Details
Reaction catalysed:
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domains:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157377 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Tyrosine-protein phosphatase non-receptor type 11
Molecule details ›
Chain: A
Length: 220 amino acids
Theoretical weight: 24.82 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
Sequence domains: SH2 domain
Structure domains: SH2 domain
Length: 220 amino acids
Theoretical weight: 24.82 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
- Canonical:
Q06124 (Residues: 1-220; Coverage: 37%)
Sequence domains: SH2 domain
Structure domains: SH2 domain
Cytotoxicity-associated immunodominant antigen
Molecule details ›
Chains: L, N
Length: 13 amino acids
Theoretical weight: 1.51 KDa
Source organism: Helicobacter pylori
Expression system: Not provided
UniProt:
Sequence domains: CagA exotoxin phosphopeptide substrate mimic region
Length: 13 amino acids
Theoretical weight: 1.51 KDa
Source organism: Helicobacter pylori
Expression system: Not provided
UniProt:
- Canonical: P55980 (Residues: 966-978; Coverage: 1%)
Sequence domains: CagA exotoxin phosphopeptide substrate mimic region
