5x9o

X-ray diffraction
1.58Å resolution

Crystal structure of the BCL6 BTB domain in complex with Compound 1a

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
PDBe Complex ID:
PDB-CPX-154262 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
B-cell lymphoma 6 protein Chain: A
Molecule details ›
Chain: A
Length: 141 amino acids
Theoretical weight: 16.29 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P41182 (Residues: 5-129; Coverage: 18%)
Gene names: BCL5, BCL6, LAZ3, ZBTB27, ZNF51
Sequence domains: BTB/POZ domain
Structure domains: Potassium Channel Kv1.1; Chain A

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: P6122
Unit cell:
a: 66.618Å b: 66.618Å c: 151.996Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.2 0.199 0.213
Expression system: Escherichia coli