› 5xr1

Solution NMR

Structure of FLN IG21 domain in complex with C-terminal peptide of beta-2

Released:
DOI: 10.2210/pdb5xr1/pdb
PDB entry 5xr1 coloured by chain, ensemble of 20 models, front view.
PDB entry 5xr1 coloured by chain, ensemble of 20 models, side view.
PDB entry 5xr1 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Chatterjee D, Lu LZ, Bhattacharjya S

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138491 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Filamin-A; Integrin beta-2 Chain: A
Molecule details ›
Chain: A
Length: 135 amino acids
Theoretical weight: 13.76 KDa
Source organism: Homo sapiens
Expression system: BAC cloning vector attB-P[acman]-ApR-F-2-5-attB
UniProt:
  • Canonical: P05107 (Residues: 752-763; Coverage: 2%)
  • Canonical: P21333 (Residues: 2236-2329; Coverage: 4%)
Gene names: CD18, FLN, FLN1, FLNA, ITGB2, MFI7
Sequence domains: Filamin/ABP280 repeat

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 45%
Refinement method: torsion angle dynamics
Expression system: BAC cloning vector attB-P[acman]-ApR-F-2-5-attB

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