› 5y6o

X-ray diffraction
3.1Å resolution

Crystal structure of DAXX N-terminal four-helix bundle domain (4HB) in complex with ATRX

Released:
DOI: 10.2210/pdb5y6o/pdb
PDB entry 5y6o coloured by chain, front view.
PDB entry 5y6o coloured by chain, side view.
PDB entry 5y6o coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of DAXX N-terminal four-helix bundle domain (4HB) in complex with ATRX
Huang H, Patel DJ
Nat Commun (2017)

Function and Biology Details

Reaction catalysed: 
ATP + H(2)O = ADP + phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-155426 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Death domain-associated protein 6; Transcriptional regulator ATRX Chains: A, B, C, D, E, F, G, H, I
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I
Length: 119 amino acids
Theoretical weight: 13.69 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UER7 (Residues: 50-144; Coverage: 13%)
  • Canonical: P46100 (Residues: 1265-1288; Coverage: 1%)
Gene names: ATRX, BING2, DAP6, DAXX, RAD54L, XH2
Sequence domains: Daxx N-terminal Rassf1C-interacting domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P3121
Unit cell:
a: 78.666Å b: 78.666Å c: 503.215Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.227 0.224 0.297
Expression system: Escherichia coli

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