› 5yc0

X-ray diffraction
2Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137984 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Transmembrane protein gp41 Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 44 amino acids
Theoretical weight: 5.04 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Not provided
UniProt:
  • Canonical: P04578 (Residues: 538-581; Coverage: 5%)
Gene name: env
LP-46 Chains: G, H, I, P, Q, W
Molecule details ›
Chains: G, H, I, P, Q, W
Length: 31 amino acids
Theoretical weight: 3.89 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U1
Spacegroup: P1
Unit cell:
a: 34.091Å b: 53.259Å c: 59.344Å
α: 94.42° β: 96.52° γ: 90.02°
R-values:
R R work R free
0.222 0.22 0.256
Expression system: Not provided

Quick links

Citations

6 review citations

Molecular mechanism of interaction between SARS-CoV-2 and host cells and interventional therapy.
Zhang et al. (2021)
5 more

1 mention without citation

Exceptional potency and structural basis of a T1249-derived lipopeptide fusion inhibitor against HIV-1, HIV-2, and simian immunodeficiency virus.
Zhu et al. (2018)