Function and Biology Details
Reaction catalysed:
S-adenosyl-L-methionine + DNA = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-143297 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ubiquitin
Molecule details ›
Chains: A, D
Length: 75 amino acids
Theoretical weight: 8.51 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Ubiquitin family
Length: 75 amino acids
Theoretical weight: 8.51 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P0CG47 (Residues: 153-225; Coverage: 32%)
Sequence domains: Ubiquitin family
DNA (cytosine-5)-methyltransferase 1
Molecule details ›
Chain: B
Length: 250 amino acids
Theoretical weight: 27.95 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Cytosine specific DNA methyltransferase replication foci domain
Structure domains: Arc Repressor Mutant, subunit A
Length: 250 amino acids
Theoretical weight: 27.95 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P26358 (Residues: 351-599; Coverage: 15%)
Sequence domains: Cytosine specific DNA methyltransferase replication foci domain
Structure domains: Arc Repressor Mutant, subunit A
