Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Transportin-1 and RNA-binding protein FUS (preferred)
PDBe Complex ID:
PDB-CPX-152978 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Transportin-1
Molecule details ›
Chain: A
Length: 868 amino acids
Theoretical weight: 98.33 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Structure domains: Leucine-rich Repeat Variant
Length: 868 amino acids
Theoretical weight: 98.33 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q92973 (Residues: 9-344, 376-898; Coverage: 96%)
Sequence domains:
Structure domains: Leucine-rich Repeat Variant
RNA-binding protein FUS
Molecule details ›
Chain: B
Length: 73 amino acids
Theoretical weight: 7.56 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Length: 73 amino acids
Theoretical weight: 7.56 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P35637 (Residues: 456-526; Coverage: 14%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
APS BEAMLINE 19-ID
Spacegroup:
P21212
Expression system: Escherichia coli BL21(DE3)
