Function and Biology Details
Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
ATR-ATRIP DNA damage-sensing kinase complex (preferred)
PDBe Complex ID:
PDB-CPX-171743 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Serine/threonine-protein kinase ATR
Molecule details ›
Chains: A, B
Length: 2644 amino acids
Theoretical weight: 301.76 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains:
Length: 2644 amino acids
Theoretical weight: 301.76 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
Q13535 (Residues: 1-2644; Coverage: 100%)
Sequence domains:
ATR-interacting protein
Molecule details ›
Chains: C, D
Length: 791 amino acids
Theoretical weight: 85.94 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Length: 791 amino acids
Theoretical weight: 85.94 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: Q8WXE1 (Residues: 1-791; Coverage: 100%)
