Function and Biology Details
Reaction catalysed:
Endonucleolytic cleavage to 5'-phosphomonoester.
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
RISC-loading complex, TARBP2 variant and RNA (preferred)
PDBe Complex ID:
PDB-CPX-172350 (preferred)
Entry contents:
2 distinct polypeptide molecules
1 distinct RNA molecule
1 distinct RNA molecule
Macromolecules (3 distinct):
Endoribonuclease Dicer
Molecule details ›
RISC-loading complex subunit TARBP2
Molecule details ›
Chain: B
Length: 366 amino acids
Theoretical weight: 39.09 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: Double-stranded RNA binding motif
Length: 366 amino acids
Theoretical weight: 39.09 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
Q15633 (Residues: 1-366; Coverage: 100%)
Sequence domains: Double-stranded RNA binding motif
