› 5znd

X-ray diffraction
3Å resolution

8-mer nanotube derived from 24-mer rHuHF nanocage

Released:
DOI: 10.2210/pdb5znd/pdb
PDB entry 5znd coloured by chain, front view.
PDB entry 5znd coloured by chain, side view.
PDB entry 5znd coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Selective Elimination of the Key Subunit Interfaces Facilitates Conversion of Native 24-mer Protein Nanocage into 8-mer Nanorings.
Wang W, Wang L, Chen H, Zang J, Zhao X, Zhao G, Wang H
J Am Chem Soc 140 14078-14081 (2018)
PMID: 30336004

Function and Biology Details

Reaction catalysed: 
4 Fe(2+) + 4 H(+) + O(2) = 4 Fe(3+) + 2 H(2)O
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo octamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136247 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ferritin heavy chain, N-terminally processed Chain: A
Molecule details ›
Chain: A
Length: 134 amino acids
Theoretical weight: 15.76 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P02794 (Residues: 1-134; Coverage: 73%)
Gene names: FTH, FTH1, FTHL6, OK/SW-cl.84, PIG15
Sequence domains: Ferritin-like domain
Structure domains: Ferritin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U1
Spacegroup: I422
Unit cell:
a: 100.352Å b: 100.352Å c: 51.712Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.232 0.227 0.276
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Protein Assembly by Design.
Zhu et al. (2021)
3 more