Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero pentamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172408 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Mothers against decapentaplegic homolog 2
Molecule details ›
Chains: A, B, C
Length: 200 amino acids
Theoretical weight: 22.52 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: MH2 domain
Structure domains: Tumour Suppressor Smad4
Length: 200 amino acids
Theoretical weight: 22.52 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q15796 (Residues: 262-458; Coverage: 42%)
Sequence domains: MH2 domain
Structure domains: Tumour Suppressor Smad4
Inner nuclear membrane protein Man1
Molecule details ›
Chains: D, E
Length: 132 amino acids
Theoretical weight: 14.97 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Length: 132 amino acids
Theoretical weight: 14.97 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: Q9Y2U8 (Residues: 762-890; Coverage: 14%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
PHOTON FACTORY BEAMLINE AR-NE3A
Spacegroup:
P65
Expression system: Escherichia coli
