Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172412 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Mothers against decapentaplegic homolog 1
Molecule details ›
Chains: A, C
Length: 209 amino acids
Theoretical weight: 23.65 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: MH2 domain
Structure domains: Tumour Suppressor Smad4
Length: 209 amino acids
Theoretical weight: 23.65 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q15797 (Residues: 259-462; Coverage: 44%)
Sequence domains: MH2 domain
Structure domains: Tumour Suppressor Smad4
Inner nuclear membrane protein Man1
Molecule details ›
Chains: B, D
Length: 132 amino acids
Theoretical weight: 14.97 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Length: 132 amino acids
Theoretical weight: 14.97 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: Q9Y2U8 (Residues: 762-890; Coverage: 14%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
RIGAKU FR-E SUPERBRIGHT
Spacegroup:
P4132
Expression system: Escherichia coli
