Function and Biology Details
Reaction catalysed:
Hydrolysis of an N(6)-acetyl-lysine residue of a histone to yield a deacetylated histone
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157482 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Histone deacetylase 4
Molecule details ›
Chain: G
Length: 399 amino acids
Theoretical weight: 43 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Histone deacetylase domain
Structure domains: Histone deacetylase domain
Length: 399 amino acids
Theoretical weight: 43 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P56524 (Residues: 652-1050; Coverage: 37%)
Sequence domains: Histone deacetylase domain
Structure domains: Histone deacetylase domain
Nuclear receptor corepressor 2
Molecule details ›
Chain: A
Length: 12 amino acids
Theoretical weight: 1.29 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Length: 12 amino acids
Theoretical weight: 1.29 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: Q9Y618 (Residues: 1448-1459; Coverage: 1%)
