Function and Biology Details
Reactions catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
1-phosphatidyl-1D-myo-inositol 3,4,5-triphosphate + H(2)O = 1-phosphatidyl-1D-myo-inositol 3,4-diphosphate + phosphate
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domains:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-169849 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ephrin type-A receptor 2; Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2
Molecule details ›
Chains: A, B
Length: 159 amino acids
Theoretical weight: 17.62 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
Sequence domains: SAM domain (Sterile alpha motif)
Length: 159 amino acids
Theoretical weight: 17.62 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
- Canonical:
Q6P549 (Residues: 1200-1257; Coverage: 5%) - Canonical: Q03145 (Residues: 900-977; Coverage: 8%)
Sequence domains: SAM domain (Sterile alpha motif)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
SSRF BEAMLINE BL17U1
Spacegroup:
C2
Expression system: Escherichia coli
