› 5azw

X-ray diffraction
1.5Å resolution

Crystal structure of p24beta1 GOLD domain

Released:
DOI: 10.2210/pdb5azw/pdb
PDB entry 5azw coloured by chain, front view.
PDB entry 5azw coloured by chain, side view.
PDB entry 5azw coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
3D Structure and Interaction of p24β and p24δ Golgi Dynamics Domains: Implication for p24 Complex Formation and Cargo Transport.
Nagae M, Hirata T, Morita-Matsumoto K, Theiler R, Fujita M, Kinoshita T, Yamaguchi Y
J Mol Biol 428 4087-4099 (2016)
PMID: 27569046

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172260 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transmembrane emp24 domain-containing protein 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 96 amino acids
Theoretical weight: 10.67 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q15363 (Residues: 19-114; Coverage: 52%)
Gene names: RNP24, TMED2
Sequence domains: emp24/gp25L/p24 family/GOLD

Ligands and Environments

1 bound ligand:
Ligand EDO 2 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE AR-NW12A
Spacegroup: C2
Unit cell:
a: 97.772Å b: 35.664Å c: 62.312Å
α: 90° β: 129.22° γ: 90°
R-values:
R R work R free
0.221 0.221 0.233
Expression system: Escherichia coli

Quick links

Citations

6 review citations

TMP21 in Alzheimer's Disease: Molecular Mechanisms and a Potential Target.
Qiu et al. (2019)
5 more

3 mentions without citation

Control of anterior GRadient 2 (AGR2) dimerization links endoplasmic reticulum proteostasis to inflammation.
Maurel et al. (2019)
2 more