› 5ctq

X-ray diffraction
2.6Å resolution

Crystal structure of human SART3/TIP110 half-a TPR (HAT) domain

Released:
DOI: 10.2210/pdb5ctq/pdb
PDB entry 5ctq coloured by chain, front view.
PDB entry 5ctq coloured by chain, side view.
PDB entry 5ctq coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural basis for recruiting and shuttling of the spliceosomal deubiquitinase USP4 by SART3.
Park JK, Das T, Song EJ, Kim EE
Nucleic Acids Res 44 5424-37 (2016)
PMID: 27060135

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172162 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Squamous cell carcinoma antigen recognized by T-cells 3 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 561 amino acids
Theoretical weight: 65.82 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q15020 (Residues: 94-611; Coverage: 54%)
Gene names: KIAA0156, SART3, TIP110

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 5C (4A)
Spacegroup: P21
Unit cell:
a: 120.912Å b: 80.529Å c: 146.641Å
α: 90° β: 99.36° γ: 90°
R-values:
R R work R free
0.236 0.235 0.281
Expression system: Escherichia coli

Quick links

Citations

8 review citations

The life of U6 small nuclear RNA, from cradle to grave.
Didychuk et al. (2018)
7 more

2 mentions without citation

Structural basis for recruiting and shuttling of the spliceosomal deubiquitinase USP4 by SART3.
Park et al. (2016)
1 more