5d7g

X-ray diffraction
3Å resolution

Structure of human ATG5 E122D-ATG16L1 complex at 3.0 Angstroms

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-179298 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Autophagy protein 5 Chains: A, C, E, G
Molecule details ›
Chains: A, C, E, G
Length: 280 amino acids
Theoretical weight: 32.88 KDa
Source organism: Homo sapiens
Expression system: Baculovirus expression vector pFastBac1-HM
UniProt:
  • Canonical: Q9H1Y0 (Residues: 1-275; Coverage: 100%)
Gene names: APG5L, ASP, ATG5
Sequence domains:
Structure domains:
Autophagy-related protein 16-1 Chains: B, D, F, H
Molecule details ›
Chains: B, D, F, H
Length: 71 amino acids
Theoretical weight: 8.49 KDa
Source organism: Homo sapiens
Expression system: Baculovirus expression vector pFastBac1-HM
UniProt:
  • Canonical: Q676U5 (Residues: 1-69; Coverage: 11%)
Gene names: APG16L, ATG16L1, UNQ9393/PRO34307

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: C2
Unit cell:
a: 217.114Å b: 84.478Å c: 151.849Å
α: 90° β: 133.81° γ: 90°
R-values:
R R work R free
0.2 0.198 0.244
Expression system: Baculovirus expression vector pFastBac1-HM