› 5dof

X-ray diffraction
1.7Å resolution

Crystal structure of Tetrahymena p19

Released:
DOI: 10.2210/pdb5dof/pdb
PDB entry 5dof coloured by chain, front view.
PDB entry 5dof coloured by chain, side view.
PDB entry 5dof coloured by chain, top view.
Source organism: Tetrahymena thermophila
Primary publication:
The Tetrahymena telomerase p75-p45-p19 subcomplex is a unique CST complex.
Wan B, Tang T, Upton H, Shuai J, Zhou Y, Li S, Chen J, Brunzelle JS, Zeng Z, Collins K, Wu J, Lei M
Nat Struct Mol Biol 22 1023-6 (2015)
PMID: 26551074

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo tetramer
Assembly name:
PDBe Complex ID:
PDB-CPX-112351 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Telomerase-associated protein of 19 kDa Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 163 amino acids
Theoretical weight: 19.41 KDa
Source organism: Tetrahymena thermophila
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: D2CVN7 (Residues: 2-164; Coverage: 99%)
Gene names: TAP19, TTHERM_00658760

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 4 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-D
Spacegroup: P21
Unit cell:
a: 40.732Å b: 128.631Å c: 75.328Å
α: 90° β: 105.05° γ: 90°
R-values:
R R work R free
0.179 0.177 0.22
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

12 review citations

Telomerase Mechanism of Telomere Synthesis.
Wu et al. (2017)
11 more

5 mentions without citation

Assessment of movement quality in robot- assisted upper limb rehabilitation after stroke: a review.
Nordin et al. (2014)
4 more