› 5fm8

X-ray diffraction
2.05Å resolution

Structure of the C-terminally extended domain My4 of human myomesin (space group P65)

Released:
DOI: 10.2210/pdb5fm8/pdb
PDB entry 5fm8 coloured by chain, front view.
PDB entry 5fm8 coloured by chain, side view.
PDB entry 5fm8 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Binding of Myomesin to Obscurin-Like-1 at the Muscle M-Band Provides a Strategy for Isoform-Specific Mechanical Protection.
Pernigo S, Fukuzawa A, Beedle AEM, Holt M, Round A, Pandini A, Garcia-Manyes S, Gautel M, Steiner RA
Structure 25 107-120 (2017)
PMID: 27989621

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156475 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Myomesin-1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 112 amino acids
Theoretical weight: 12.19 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P52179 (Residues: 510-618; Coverage: 7%)
Gene name: MYOM1
Sequence domains: Fibronectin type III domain
Structure domains: Immunoglobulins

Ligands and Environments

2 bound ligands:
Ligand NI 2 x NI
Ligand TRS 1 x TRS
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P65
Unit cell:
a: 97.41Å b: 97.41Å c: 106.15Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.194 0.192 0.217
Expression system: Escherichia coli

Quick links

Citations

5 review citations

Skeletal muscle: A review of molecular structure and function, in health and disease.
Mukund et al. (2020)
4 more

1 mention without citation

Binding of Myomesin to Obscurin-Like-1 at the Muscle M-Band Provides a Strategy for Isoform-Specific Mechanical Protection.
Pernigo et al. (2017)