› 5gyq

X-ray diffraction
2.1Å resolution

Putative receptor-binding domain of bat-derived coronavirus HKU9 spike protein

Released:
DOI: 10.2210/pdb5gyq/pdb
PDB entry 5gyq coloured by chain, front view.
PDB entry 5gyq coloured by chain, side view.
PDB entry 5gyq coloured by chain, top view.
Source organism: Rousettus bat coronavirus HKU9
Primary publication:
Putative Receptor Binding Domain of Bat-Derived Coronavirus HKU9 Spike Protein: Evolution of Betacoronavirus Receptor Binding Motifs.
Huang C, Qi J, Lu G, Wang Q, Yuan Y, Wu Y, Zhang Y, Yan J, Gao GF
Biochemistry 55 5977-5988 (2016)
PMID: 27696819

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-107109 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Spike protein S1 Chain: A
Molecule details ›
Chain: A
Length: 176 amino acids
Theoretical weight: 19.87 KDa
Source organism: Rousettus bat coronavirus HKU9
Expression system: Trichoplusia ni
UniProt:
  • Canonical: A3EXG6 (Residues: 355-521; Coverage: 13%)
Gene names: 2, S
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P21
Unit cell:
a: 42.752Å b: 35.99Å c: 62.886Å
α: 90° β: 102.72° γ: 90°
R-values:
R R work R free
0.172 0.17 0.201
Expression system: Trichoplusia ni

Quick links

Citations

5 review citations

How Nanophotonic Label-Free Biosensors Can Contribute to Rapid and Massive Diagnostics of Respiratory Virus Infections: COVID-19 Case.
Soler et al. (2020)
4 more

3 mentions without citation

Crystal structure of the receptor binding domain of the spike glycoprotein of human betacoronavirus HKU1.
Ou et al. (2017)
2 more