› 5hb6

X-ray diffraction
1.3Å resolution

Crystal structure of Chaetomium thermophilum Nup145N APD T994A mutant fused to Nup145C N

Released:
DOI: 10.2210/pdb5hb6/pdb
PDB entry 5hb6 coloured by chain, front view.
PDB entry 5hb6 coloured by chain, side view.
PDB entry 5hb6 coloured by chain, top view.
Source organism: Chaetomium thermophilum var. thermophilum DSM 1495
Primary publication:
Architecture of the symmetric core of the nuclear pore.
Lin DH, Stuwe T, Schilbach S, Rundlet EJ, Perriches T, Mobbs G, Fan Y, Thierbach K, Huber FM, Collins LN, Davenport AM, Jeon YE, Hoelz A
Science 352 aaf1015 (2016)
PMID: 27081075

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-124050 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nucleoporin NUP145C Chains: A, B
Molecule details ›
Chains: A, B
Length: 144 amino acids
Theoretical weight: 16.04 KDa
Source organism: Chaetomium thermophilum var. thermophilum DSM 1495
Expression system: Escherichia coli
UniProt:
  • Canonical: G0SAK3 (Residues: 858-1000; Coverage: 8%)
Gene names: CTHT_0042590, NUP145
Sequence domains: Nucleoporin autopeptidase
Structure domains: Peptidase S59, nucleoporin

Ligands and Environments

1 bound ligand:
Ligand SO4 5 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.2
Spacegroup: P1
Unit cell:
a: 43.018Å b: 44.12Å c: 45.336Å
α: 99.76° β: 110.98° γ: 105.91°
R-values:
R R work R free
0.151 0.151 0.174
Expression system: Escherichia coli

Quick links

Citations

41 review citations

The nuclear pore complex: understanding its function through structural insight.
Beck et al. (2017)
40 more

2 mentions without citation

Architecture of the symmetric core of the nuclear pore.
Lin et al. (2016)
1 more