› 5hgc

X-ray diffraction
2.43Å resolution

A Serpin structure

Released:
DOI: 10.2210/pdb5hgc/pdb
PDB entry 5hgc coloured by chain, front view.
PDB entry 5hgc coloured by chain, side view.
PDB entry 5hgc coloured by chain, top view.
Source organism: Taeniopygia guttata
Primary publication:
A Serpin structure
Vashchenko GV, Das S, Moon K-M, Rogalski JC, Taves MD, Soma KK, Van Petegem F, Foster LJ, Hammond GL
J. Biol. Chem. (2016)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo trimer
Assembly name:
PDBe Complex ID:
PDB-CPX-124717 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serpin domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 380 amino acids
Theoretical weight: 42.93 KDa
Source organism: Taeniopygia guttata
Expression system: Escherichia coli
UniProt:
  • Canonical: H0ZQY2 (Residues: 46-381, 382-384; Coverage: 85%)
Sequence domains: Serpin (serine protease inhibitor)
Structure domains:

Ligands and Environments

3 bound ligands:
Ligand HCY 1 x HCY
Ligand SO4 4 x SO4
Ligand BDG 1 x BDG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: P63
Unit cell:
a: 116.15Å b: 116.15Å c: 72.73Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.164 0.162 0.217
Expression system: Escherichia coli

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Citations

1 review citation

Environmental Endocrinology: Insights into the Diversity of Regulatory Mechanisms in Life Cycles.
Wingfield JC. (2018)
5 other articles

3 mentions without citation

Avian corticosteroid-binding globulin: biological function and regulatory mechanisms in physiological stress responses.
Lin et al. (2021)
2 more