› 5ijx

X-ray diffraction
2.63Å resolution

Crystal Structure of a C-terminally truncated Coccidioides posadasii mitochondrial tyrosyl-tRNA synthetase

Released:
DOI: 10.2210/pdb5ijx/pdb
PDB entry 5ijx coloured by chain, front view.
PDB entry 5ijx coloured by chain, side view.
PDB entry 5ijx coloured by chain, top view.
Source organism: Coccidioides posadasii C735 delta SOWgp
Entry authors: Lamech LT, Lambowitz AM

Function and Biology Details

Reaction catalysed: 
ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + L-tyrosyl-tRNA(Tyr)
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-111531 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tyrosine--tRNA ligase Chain: A
Molecule details ›
Chain: A
Length: 384 amino acids
Theoretical weight: 44.13 KDa
Source organism: Coccidioides posadasii C735 delta SOWgp
Expression system: Escherichia coli
UniProt:
  • Canonical: C5P455 (Residues: 47-429; Coverage: 60%)
Gene name: CPC735_063460
Sequence domains: tRNA synthetases class I (W and Y)
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand TYR 1 x TYR
1 modified residue:
Ligand MSE 11 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-G
Spacegroup: C2
Unit cell:
a: 117.173Å b: 75.785Å c: 52.316Å
α: 90° β: 94.55° γ: 90°
R-values:
R R work R free
0.208 0.206 0.236
Expression system: Escherichia coli

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