Function and Biology Details
Reaction catalysed:
The C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Endonuclease 8-like 1 and DNA (preferred)
PDBe Complex ID:
PDB-CPX-118805 (preferred)
Entry contents:
2 distinct polypeptide molecules
1 distinct DNA molecule
1 distinct DNA molecule
Macromolecules (3 distinct):
Endonuclease 8-like 1
Molecule details ›
Chains: A, B
Length: 390 amino acids
Theoretical weight: 43.76 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains:
Structure domains:
Length: 390 amino acids
Theoretical weight: 43.76 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q96FI4 (Residues: 1-390; Coverage: 100%)
Sequence domains:
Structure domains:
Endonuclease 8-like 1
Molecule details ›
Chain: E
Length: 400 amino acids
Theoretical weight: 44.89 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains:
Structure domains:
Length: 400 amino acids
Theoretical weight: 44.89 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: Q96FI4 (Residues: 1-390; Coverage: 100%)
Sequence domains:
Structure domains:
