› 5jeu

X-ray diffraction
0.97Å resolution

del-[Ru(phen)2(dppz)]2+ bound to d(TCGGCGCCGA) with Ba2+

Released:
DOI: 10.2210/pdb5jeu/pdb
PDB entry 5jeu coloured by chain, front view.
PDB entry 5jeu coloured by chain, side view.
PDB entry 5jeu coloured by chain, top view.
Source organism: synthetic construct
Primary publication:
Delta chirality ruthenium 'light-switch' complexes can bind in the minor groove of DNA with five different binding modes.
Hall JP, Keane PM, Beer H, Buchner K, Winter G, Sorensen TL, Cardin DJ, Brazier JA, Cardin CJ
Nucleic Acids Res 44 9472-9482 (2016)
PMID: 27599841

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-118867 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
DNA (5'-D(*TP*CP*GP*GP*CP*GP*CP*CP*GP*A)-3') Chain: A
Molecule details ›
Chain: A
Length: 10 nucleotides
Theoretical weight: 3.05 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

3 bound ligands:
Ligand BA 1 x BA
Ligand 0TN 2 x 0TN
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I02
Spacegroup: P41212
Unit cell:
a: 48.62Å b: 48.62Å c: 29.43Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.113 0.112 0.127
Expression system: Not provided

Quick links

Citations

3 review citations

The development of ruthenium(ii) polypyridyl complexes and conjugates for in vitro cellular and in vivo applications.
Poynton et al. (2017)
2 more

3 mentions without citation

A survey of recent unusual high-resolution DNA structures provoked by mismatches, repeats and ligand binding.
Satange et al. (2018)
2 more