Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Neurotransmitter-gated ion-channel
- Nicotinic acetylcholine receptor
- Neurotransmitter-gated ion-channel transmembrane domain
- Neurotransmitter-gated ion-channel ligand-binding domain superfamily
- Neuronal acetylcholine receptor
- Neurotransmitter-gated ion-channel transmembrane domain superfamily
- Neurotransmitter-gated ion-channel, conserved site
- Neurotransmitter-gated ion-channel ligand-binding domain
Structure analysis Details
Assembly composition:
hetero pentamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148175 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Neuronal acetylcholine receptor subunit alpha-4
Molecule details ›
Chains: A, D
Length: 386 amino acids
Theoretical weight: 44.86 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains:
Length: 386 amino acids
Theoretical weight: 44.86 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
P43681 (Residues: 27-364, 586-627; Coverage: 63%)
Sequence domains:
Neuronal acetylcholine receptor subunit beta-2
Molecule details ›
Chains: B, C, E
Length: 403 amino acids
Theoretical weight: 46.75 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains:
Length: 403 amino acids
Theoretical weight: 46.75 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: P17787 (Residues: 26-355, 446-502; Coverage: 81%)
Sequence domains:
