› 5lpc

X-ray diffraction
3.1Å resolution

Crystal structure of Vanadium-dependent Haloperoxidase from A. marina

Released:
DOI: 10.2210/pdb5lpc/pdb
PDB entry 5lpc coloured by chain, front view.
PDB entry 5lpc coloured by chain, side view.
PDB entry 5lpc coloured by chain, top view.
Source organism: Acaryochloris marina
Primary publication:
Characterization of a Cyanobacterial Haloperoxidase and Evaluation of its Biocatalytic Halogenation Potential.
Frank A, Seel CJ, Groll M, Gulder T
Chembiochem 17 2028-2032 (2016)
PMID: 27542168

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dodecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-109126 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Vanadium-dependent bromoperoxidase, putative Chain: A
Molecule details ›
Chain: A
Length: 666 amino acids
Theoretical weight: 73.07 KDa
Source organism: Acaryochloris marina
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: B0C4R0 (Residues: 1-639; Coverage: 100%)
Gene name: AM1_4975
Structure domains: Vanadium-containing Chloroperoxidase, domain 2

Ligands and Environments

1 bound ligand:
Ligand PO4 1 x PO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: F4132
Unit cell:
a: 306.16Å b: 306.16Å c: 306.16Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.209 0.207 0.249
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

4 review citations

Biocatalytic Oxidation Reactions: A Chemist's Perspective.
Dong et al. (2018)
3 more

3 mentions without citation

Halogenases: a palette of emerging opportunities for synthetic biology-synthetic chemistry and C-H functionalisation.
Crowe et al. (2021)
2 more