5m5s

X-ray diffraction
1.88Å resolution

Clathrin heavy chain N-terminal domain bound to amphiphysin clathrin-box motif

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-155946 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Clathrin heavy chain 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 365 amino acids
Theoretical weight: 40.54 KDa
Source organism: Bos taurus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P49951 (Residues: 1-363; Coverage: 22%)
Gene name: CLTC
Sequence domains:
Structure domains: Clathrin heavy-chain terminal domain
Amphiphysin Chains: E, F, G, H
Molecule details ›
Chains: E, F, G, H
Length: 10 amino acids
Theoretical weight: 1.18 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P49418 (Residues: 349-358; Coverage: 1%)
Gene names: AMPH, AMPH1

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: C2
Unit cell:
a: 139.967Å b: 134.11Å c: 78.012Å
α: 90° β: 115.07° γ: 90°
R-values:
R R work R free
0.206 0.204 0.234
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided