› 5mix

X-ray diffraction
1.7Å resolution

Extracellular domain of human CD83 - trigonal crystal form

Released:
DOI: 10.2210/pdb5mix/pdb
PDB entry 5mix coloured by chain, front view.
PDB entry 5mix coloured by chain, side view.
PDB entry 5mix coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal Structure of the Extracellular Domain of the Human Dendritic Cell Surface Marker CD83.
Heilingloh CS, Klingl S, Egerer-Sieber C, Schmid B, Weiler S, Mühl-Zürbes P, Hofmann J, Stump JD, Sticht H, Kummer M, Steinkasserer A, Muller YA
J Mol Biol 429 1227-1243 (2017)
PMID: 28315353

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-169529 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
CD83 antigen Chain: A
Molecule details ›
Chain: A
Length: 116 amino acids
Theoretical weight: 12.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q01151 (Residues: 20-131; Coverage: 60%)
Gene name: CD83
Sequence domains: Immunoglobulin V-set domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P321
Unit cell:
a: 62.942Å b: 62.942Å c: 40.064Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.191 0.188 0.216
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

3 review citations

The CD83 Molecule - An Important Immune Checkpoint.
Grosche et al. (2020)
2 more