› 5my7

X-ray diffraction
1.4Å resolution

Adhesin Complex Protein from Neisseria meningitidis

Released:
DOI: 10.2210/pdb5my7/pdb
PDB entry 5my7 coloured by chain, front view.
PDB entry 5my7 coloured by chain, side view.
PDB entry 5my7 coloured by chain, top view.
Source organism: Neisseria meningitidis
Primary publication:
Structure of the Neisseria Adhesin Complex Protein (ACP) and its role as a novel lysozyme inhibitor.
Humbert MV, Awanye AM, Lian LY, Derrick JP, Christodoulides M
PLoS Pathog 13 e1006448 (2017)
PMID: 28662181

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-191673 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Adhesin complex protein Chain: A
Molecule details ›
Chain: A
Length: 124 amino acids
Theoretical weight: 13.31 KDa
Source organism: Neisseria meningitidis
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9JXD8 (Residues: 1-124; Coverage: 100%)
Gene name: NMB2095

Ligands and Environments

2 bound ligands:
Ligand PEG 2 x PEG
Ligand NA 1 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: P3221
Unit cell:
a: 58.47Å b: 58.47Å c: 51.561Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.162 0.16 0.2
Expression system: Escherichia coli

Quick links

Citations

7 review citations

From bacterial killing to immune modulation: Recent insights into the functions of lysozyme.
Ragland et al. (2017)
6 more

2 mentions without citation

Structure of the Recombinant Neisseria gonorrhoeae Adhesin Complex Protein (rNg-ACP) and Generation of Murine Antibodies with Bactericidal Activity against Gonococci.
Almonacid-Mendoza et al. (2018)
1 more